AB1555 CORRELATION BETWEEN HIGH RESOLUTION CHEST TOMOGRAPHY AND CAPILLAROSCOPIC FINDINGS IN SYSTEMIC SCLEROSIS

Background Systemic sclerosis (SSc) is a chronic autoimmune multisystemic disease characterized by fibrosis and vasculopathy. [1] Mortality in patients with systemic who present interstitial lung can be up to 3x healthy population. [2] It estimated that 70-90% have disease. [3] High resolution computed tomography (HRCT) of chest recognized as sensitive imaging method for evaluating pulmonary involvement. [4,5] Presentation patterns are also described: NSIP (non specific pneumonia), UIP (usual COP (cryptogenic organizing LIP (Lymphocytic pneumonitis). Capillaroscopy allows the study microcirculation. Changes classified into “early,” “active,” “late” scleroderma patterns. [6] Objectives To relate between high capillaroscopic findings sclerosis. Methods Descriptive, observational, cross-sectional study. Optilia CapiScope 2.0/5.0MP ultrasound Siemmens Acuson X150 were performed SSc outpatient clinic rheumatology service from August-November 2021. Inclusion criteria: > 18 years old, meet criteria classification according ACR/EULAR 2013. Exclusion history pre-existing Results 22 met inclusion criteria. 80% female. Diffuse 81.8% (18), limited 18.2% (4). Mean age 54±17 years, duration 58.1% (13) >5 40.9% (9) < 5 mean diagnosis 15.3±9.2 mRSS 19.4 + 13.2 Mild: 22.7% (5), moderate (4), severe 27.3% (6), terminal 31.8% (7). ANA+ 45.5% (10), Topo IA Treatment: RTX 77.3% (17), Ca+ antagonists 68.2% (15), Bosentan 36.4% (8), MMF Colchicine (7), Sildenafil (6). Capillaroscopy: normal pattern 59% (13), early 9.1% (2), active 4.5% (1), late nonspecific abnormalities (1). TACAR: 54.5% (12) normal, pathological 45.4% (10): 20% (2). TACAR/Capillaroscopy correlation: (1) rp=.112, rp=.769, capillaroscopy rp=. 518, 27.2% (6) rp=1, TACAR rp=.622, Conclusion We found this correlated greater recommended follow existence or not evaluate response medication. References [1]Morrisroe K, Stevens W, Sahhar J. The clinical economic burden related Rheumatology. 2019;0(1):1-11. [2]Volkmann E, Tashkin D, Sim M, Kim G, Goldin J, Clements P. Determining progression scleroderma-related Journal Scleroderma Related Disorders. 2018;4(1):62-70. [3]Simeón-Aznar C, Fonollosa-Plá V, et al. Registry Spanish Network forSystemic Sclerosis. Medicine. 2015;94(43):e1728. [4]Hussein, K., Shaaban, L. Mohamed, E., 2016. Correlation CT function tests diseases. Egyptian Chest Diseases Tuberculosis, 65(3), pp.681- 688. [5]Chung JH, Walker CM, Hobbs S. Imaging Features Sclerosis- Associated Interstitial Lung Disease. J Vis Exp. 2020 [6]Man, M., Dantes, Domokos Hancu, B., Bondor, C., Ruscovan, A., Parau, Motoc, N. Marc, 2019. Transthoracic Ultrasound Score HRCT Patients Diseases. Clinical Medicine, 8(8), p.1199. Acknowledgements: NIL. Disclosure Interests None Declared.